Best segment/automation setup for a niche content site's newsletter?

Hi everyone, I run a niche content website (crabguide.com) focused on pet hermit crab care and seafood recipes, and I'm setting up my first email newsletter through Constant Contact. I have two very different reader types, pet owners and home cooks, and I want to avoid sending irrelevant content to either group.

Would you recommend starting with separate lists/segments from day one, or using tags on a single list and filtering later? Also open to tips on a good welcome automation for a brand-new niche blog audience.

Thanks in advance!

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