Hello @FirstNameL10623 ,
By "listings" are you referring to real estate listings - as in content and links you want to include in your email? Or by "listings" are you referring to contact lists?
If the former, you'd presumably be having these listings explicitly setup as separate articles / sections of images and text, each with a button or some other link method that can be tracked. The email's click report and heat map will show you which links were most popularly clicked, how many clicks it got, etc. To take this further, if you're only wanting to send a single email with different content showing depending on specific contact elements (e.g. Zip Code or City), then you could utilize Dynamic Content - a Plus plan feature.
If the latter, you could utilize contact segmentation afterwards, with criteria set for a specific list membership AND Contact Activity of opening/clicking in the specific email. However the easiest (and most straightforward) methodology to keep them all separate would be to simply create your email, copy it however many times you need, then schedule each individual copy to send to its respective list at the same date/time.
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