Hello @user016021 ,
There isn't an "exclude list" option regardless of account size, it would require using segmentation. When setting up the segmentation, you'd be wanting to do it with the following criteria:
List Membership > Is > select the list you'd be sending to
AND
List Membership > Is Not > the list explicitly made for excluding contacts that have already donated.
Once the segment is done calculating, it will present the contacts that are on your main list, and exclude the ones you've added to your already donated list. Then you'd send your email to this segment. Each time you add to your already-donated list, and send to the segment, it will recalculate to ensure the most up-to-date info is being considered.
If you're particularly concerned, you can also click on the segment name in your Contacts dashboard to force a manual recalculation after updating your already-donated list. You can also make a list from the current version of the segment, and send to that instead. Additionally, keep in mind that the more contacts there are being calculated for the segment, the longer it may take to process, which can lead to some minor delays in sending.
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