Hello @KathyZ8 ,
You can edit an email's reply-to address in the email builder by clicking on the header area, or when you're scheduling the email. Any addresses verified on your account will be available to select for a reply-to address.
For instructions on removing the former employee's address, where potentially applicable, your account owner can follow along with these guides (also available via the Help tab in your account):
Removing verified addresses
Removing users
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