Hello @SarahE86 ,
The point of Account Managers is to be able to handle most account functionalities, with some standard restrictions that only the Owner can do. However they would all operate under the same account, it doesn't give them special access or email / contact management that other managers and the owner wouldn't also have. For a full rundown of what managers can do, please see this article.
For a rundown of what the Campaign Creator permission level can do, please see this article.
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When a contact unsubscribes, they're unsubscribing from all of your lists. This is done reasonably straightforward to ensure compliance with various anti-spam laws, federal and international.
Using the Update Profile system, you can include this as an alternative link in your email footer, which contacts can select to update their list membership, based on the lists you make viewable and editable. If multiple list options are available in your UP form, those options will also appear on the unsubscription confirmation page, as an alternative for contacts that click the unsub link in the footer.
Remember that not all lists need to be included in the UP / unsub setup. Contacts will only be able to manipulate their list membership for the ones you've explicitly selected to be available, viewable options. Contacts will simply see those available lists' names on the UP form / unsub confirmation page, and be able to decide if they'd prefer one of those. So, in your case, you'd probably want to setup your email lists to be based on how often you would be sending to them - e.g. "Daily" list for daily sendouts, "Weekly" for once-a-week, "Bi-weekly" for once every other week, "Monthly," "Only Holiday Specials," etc.
See also:
Unsubscribed contacts overview
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